Telomeres, Telomerase and Senolytics

Telomeres, Telomerase and Senolytics

Telomeres, telomerase and senolytics is ushering in a new era of longevity medicine and vital health.   These are exciting times. In 1994 the first ever world conference on Anti-Aging Medicine was held in small “off the strip” hotel in Las Vegas.  An exciting prospect under the auspices of American Academy on Anti-Aging Medicine (A4M).  The goal of that time was to aggregate the best of medical science and information into a cohesive body of high-tech preventive medicine.  With the aim…

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Estrogen and Migraine Headaches

Estrogen and Migraine Headaches

Does estrogen benefit or exacerbate migraine headaches? Common knowledge in the medical literature is that estrogen may increase the frequency and severity of migraine headaches. This has not been our experience. Estrogen is a vasodilator.  And, therefore, should prevent the constricted phase of migraine headaches. So let me tell you a clinical story.  A 52-year-old postmenopausal female patient went to see her gynecologist. On pelvic ultrasound her endometrial (uterine lining) thickness was 4 mm. At her age a “normal” endometrial…

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Relative Risk vs Absolute Risk Reduction

Relative Risk vs Absolute Risk Reduction

I have written often and spoken repeatedly to so many of my patients about relative versus absolute risk.  This is so widespread in the medical literature, scientific literature and even in all advertising.  I am always waiting for that “aha moment” when you understand how relative risk management is chicanery.  It is used to sell you product.  To amplify, inflate or conflate results. I am prompted to write this blog by a recent meta-analysis published in JAMA Neurology May 13,…

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Is Your Body Digital or Analog?

Is Your Body Digital or Analog?

We live in a digital age.  Do you think of your body as digital or analog?  Answer this simple question.  Do you wear a modern digital watch or a traditional analog watch? Why do I ask these questions?  Because it shows how you can look at the time and space in different ways.  An analog watch does not need to be exact or precise.  A quick glance and you know exactly where you are in a diurnal 24 hour cycle. …

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Is Cholesterol the Culprit?

Is Cholesterol the Culprit?

 Probably as long as you can remember, cholesterol is “known” to be the cause of cardiovascular (heart and blood vessel) disease.  Does dietary cholesterol cause heart disease?  What about familial super high cholesterol?  Does that cause heart disease?  The short answer is – probably not.  Let’s expand.  I have written extensively on the subject in the past. Cholesterol has been studied since the early 1900s.  Initially in fits and starts. John Goffman studied cholesterol in the 1950s at Donner labs…

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2018-2019 Flu Vaccine, Prevention and Treatment

2018-2019 Flu Vaccine, Prevention and Treatment

This is my seasonal flu post.  One that I update each year.  Here are current recommendations and controversies regarding influenza vaccinations, prevention and treatment.  I am going to give you a slightly expanded version this year related to last year’s flu vaccine post.  In short, I have never been a proponent of flu vaccinations.  I am middle of road on vaccinations.  You really want polio, measles and mumps and tetanus every 10 years.  For high risk exposures you want Hepatitis…

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Vitamin D and Osteoporosis Prevention

Vitamin D and Osteoporosis Prevention

Vitamin D is back in the news again. You may have seen recent news claiming vitamin D supplementation fails to prevent osteoporosis, fractures or falls.  Published in the Lancet — a Systematic Review and Meta Analysis paper dated October 04, 2018 from the Department of Medicine, University of Auckland, New Zealand and the Health Services Research Unit, University of Aberdeen, Scotland, UK.  They conclude and state at the end of a complex meta-analysis “we believe there is no justification for…

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How CEOs respond to a cancer diagnosis

How CEOs respond to a cancer diagnosis

In a recent contribution entitled This Doctor Believes Entrepreneurs Manage a Cancer Diagnosis Better Than Most I responded with the following.  It is the substance of a much larger discussion we should have.  “I have a diagnosis of cancer.”  Now what? Cancer Risk Benefit Management All CEOs make decisions based on only 75% of the evidence. You never have 100% of the evidence. What you have stated here is that CEOs become active and not passive participants. The greatest danger of…

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Treat and Prevent Iron Deficiency Anemia

Treat and Prevent Iron Deficiency Anemia

This is the last in our series on Iron Deficiency and Iron Deficiency Anemia. In parts I, II, III, and IV, I talked about all aspects of the essentiality of iron. How to diagnose iron deficiency anemia. Various controversies surrounding iron supplementation. And the relationship of iron to various inflammatory states including cancer.  Let’s recap this series with specific treatment routines.  I encourage you to read this final wrap-up containing new and revolutionary medical paradigms. [If you want the nitty gritty,…

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Five Quick Health Tips

Five Quick Health Tips

Five Vital Health Tips Here’s a quick overview of five health recommendations that can make a huge difference in the your health and longevity. These are not easy recommendations.  But think how you can start these today. 1. Never drink tap water.  Obviously, tap water varies from locality to locality. We certainly have catastrophic examples in the past such as Love Canal and more recently Flint, Michigan. But even in the Silicon Valley the groundwater is contaminated. Toxic chemicals are…

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